Heteroaryl amines as novel acetylcholinesterase inhibitors

Details Heteroaryl amines as novel acetylcholinesterase inhibitors Heteroaryl amines as novel acetylcholinesterase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2119647

Compounds of formula (1), wherein ring A, ring B, ring D, R2, R3, R4, R5, R6, R11, R12, R13, E, G, X and P are as defined below. The compounds of formula (I) are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzeimer's disease.

Composés de formule (I), dans laquelle le cycle A, le cycle B, le cycle D, R2, R3, R4, R5, R6, R11, R12, R13, E, G, X et P correspondent aux définitions données ci-dessous. Ces composés (I) sont des inhibiteurs de la cholinestérase et sont utiles pour stimuler la mémoire chez des malades souffrant de démence ou de la maladie d'Alzeimer.

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