Integrin receptor antagonists

Details Integrin receptor antagonists Integrin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 213/30 (2006.01) C07D 235/12 (2006.01) C07D 239/26 (2006.01) C07D 257/00 (2006.01) C07D 277/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2315220

The present invention relates to compounds and derivatives thereof, their synthesis, and their use as integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors .alpha.v.beta.3, .alpha.v.beta.5, and/or .alpha.v.beta.6 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, wound healing, viral disease, tumor growth, and metastasis.

L'invention concerne des composés et des dérivés desdits composés, leurs synthèses et leur utilisation comme antagonistes du récepteur de l'intégrine. Plus particulièrement, les composés de l'invention sont des antagonistes des récepteurs alpha nu beta 3, alpha nu beta 5 et/ou alpha nu beta 6 de l'intégrine, et conviennent comme inhibiteurs de la résorption osseuse, produits de traitement ou de prévention de l'ostéoporose, de traitement des plaies, ou inhibiteurs de la resténose vasculaire, de la rétinopathie diabétique, de la dégénérescence maculaire, de l'angiogenèse, de l'athérosclérose, de l'inflammation, de maladies virales, de la croissance tumorale et de la métastase.

Affiliated with

Also associated with

Rating

Integrin receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Integrin receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Integrin receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1468425