Modifications of antigens by the introduction of aldehyde...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) C07K 1/107 (2006.01) C07K 1/113 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2329302

The invention provides a method of producing an immune response in a mammal to an antigen which comprises modifying said antigen by introducing an alkyl aldehyde group into said antigen and introducing said modified antigen into the mammal. Periodate or glycolaldehyde may be used as the agent to introduce the aldehyde groups.

L'invention concerne un procédé servant à produire une réaction immune chez un mammifère à un antigène et consistant à modifier ledit antigène par introduction d'un groupe alkylaldéhyde dans ledit antigène et à introduire ledit antigène modifié dans le mammifère. On peut utiliser périodate ou glycolaldéhyde en tant qu'agent d'introduction des groupes aldéhyde.

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