Method for treating alzheimer's disease

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A01N 33/10 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/55 (2006.01) A61K 31/58 (2006.01) A61K 38/04 (2006.01) A61K 38/06 (2006.01)

Patent

CA 2270780

A method is provided for treating occlusive vascular disease or Alzheimer's disease, wherein the patient has at least moderately elevated blood levels of homocysteine and at least moderately reduced blood levels of folate and vitamin B12, wherein the patient is treated with folic acid, a folate or a derivative thereof, and optionally vitamin B12, and optionally an organic nitrate such as isosorbide mononitrate or dinitrate, or an ACE inhibitor or an angiotensin II antagonist, or a NEP/ACE inhibitor or a combination of two or more of the above.

Méthode de traitement de la vasculopathie oblitérante ou de la maladie d'Alzheimer. Le patient atteint de l'une de ces maladies présente des taux sanguins au moins modérément élevés d'homocystéine et des taux sanguins au moins modérément réduits de folate et de vitamine B¿12?. Ladite méthode consiste à traiter le patient avec de l'acide folique, du folate ou un dérivé dudit acide, et éventuellement avec de la vitamine B¿12?, et éventuellement avec un nitrate organique tel que du mononitrate ou du dinitrate d'isosorbide, ou un inhibiteur d'enzyme de conversion de l'angiotensine (ACE) ou un antagoniste de l'angiotensine II, ou un inhibiteur d'endopeptidase neutre/ACE ou une combinaison de deux ou plusieurs desdites substances.

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