Method and apparatus for treatment of neurogenic diabetes...

A - Human Necessities – 61 – B

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A61B 17/00 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2187142

A method and implants provide for relieving pressure from a region of the brainstem within the cranium of a subject with a neuroendocrine servomechanism. The pressure results from the compression of the region by a blood vessel. The method includes gaining access to the region using a first surgical technique; exposing the region according to a second surgical technique; lifting the blood vessel from the region according to a third surgical technique, thereby providing the pressure relief; and inserting a neurovascular bridge implant between the blood vessel and the region to maintain the pressure relief. The neuroendocrine servomechanism is responsive to the pressure relief on the region, causing amelioration of a disease. One neuroendocrine servomechanism can include the pancreas of the subject, and the pressure relief ameliorates non-insulin-dependent diabetes mellitus. The neurovascular bridge implant can be a preconfigured shredded plastic implant, made of polytetrafluoroethylene, or a preconfigured thermoplastic implant, made of a polyurethane-based material having a glass-transition temperature of between 20°C to 60°C and a transition band of about 8°C.

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