A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/19 (2006.01) A61K 9/10 (2006.01) A61K 38/09 (2006.01)
Patent
CA 2589515
The invention relates to a novel method for producing sterile suspensions or lyophilisates of poorly soluble peptide complexes such as cetrorelix embonate. The invention also relates to sterile suspensions and sterile lyophilisates of poorly soluble basic peptide complexes, and to pharmaceutical formulations containing the same. Said formulations are especially suitable for using as medicaments for the treatment and prophylaxis of diseases and pathological conditions in mammals, especially humans, by parenteral administration.
L'invention concerne un nouveau procédé de production de suspensions stériles ou de lyophilisats de complexes peptidiques basiques faiblement solubles, tels que le cétrorelixembonate. L'invention concerne en outre des suspensions stériles ou des lyophilisats stériles de complexes peptidiques basiques faiblement solubles, ainsi que des formulations pharmaceutiques renfermant les composés précités. De tels produits sont appropriés pour être utilisés, en particulier, sous une forme d'administration parentérale, comme médicaments pour le traitement et la prophylaxie de maladies et d'états chroniques chez des mammifères, notamment chez l'homme.
Engel Juergen
Mueller Horst
Rischer Matthias
Werner Karl
Marks & Clerk
Zentaris Gmbh
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