Identification of compounds for modulating dimeric receptors

Details Identification of compounds for modulating dimeric receptors Identification of compounds for modulating dimeric receptors

G - Physics

01

N

G01N 33/74 (2006.01) G01N 33/68 (2006.01) G06F 17/50 (2006.01)

Patent

CA 2338678

The invention includes the fitted quaternary structure of insulin receptor. It also includes methods of identifying compounds that modulate insulin receptor activity by producing a compound that interacts with all or part of the fitted quaternary structure of insulin receptor or a fragment or derivative thereof and which thereby modulates insulin receptor activity.

L'invention concerne la structure quaternaire ajustée du récepteur de l'insuline. Cette invention concerne également des techniques d'identification de composés modulant l'activité du récepteur de l'insuline par interaction d'un composé avec tout ou partie de la structure quaternaire ajustée du récepteur de l'insuline ou un fragment ou un dérivé de celle-ci, provoquant ainsi la modulation de l'activité du récepteur de l'insuline par ce composé.

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