Soluble heterodimeric cytokine receptor

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 17/06 (2006.01)

Patent

CA 2733610

A soluble receptor that binds to IL-20 having two polypeptide subunits, IL-22R and IL-20RB. The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.

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