Lipid peroxide-lowering compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/22 (2006.01) A61K 31/16 (2006.01) A61K 31/185 (2006.01) A61K 31/195 (2006.01) A61K 31/455 (2006.01) A61K 31/465 (2006.01) A61P 3/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2428204

Compositions excellent in lowering lipid peroxides in the blood are provided. More particularly speaking, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at least one substance selected from the group consisting of taurine, panthethine and inositol hexanicotinate. Use of these compositions makes it possible to provide excellent preventives or remedies capable of lowering the concentration of lipid peroxides in the blood which show effects of injuring vascular endothelial cells, accelerating platelet aggregation, forming foam cells, etc.

L'invention concerne des compositions excellentes pour réduire la concentration de peroxydes lipidiques dans le sang. Plus précisément, l'invention concerne des compositions permettant de réduire la concentration de peroxydes lipidiques dans le sang, ces compositions renfermant de la pravastatine conjointement avec au moins une substance sélectionnée dans le groupe comprenant la taurine, la panthétine et l'inositol hexanicotinate. L'utilisation de ces compositions permettant de fournir d'excellents agents préventifs ou remèdes capables de réduire la concentration de peroxydes lipidiques dans le sang, ces agents préventifs ou remèdes présentant un effet de destruction des cellules endothéliales vasculaires, d'accélération de l'agrégation des plaquettes et de formation des cellules spumeuses, etc.

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