Novel carboxylic amides

Details Novel carboxylic amides Novel carboxylic amides

C - Chemistry, Metallurgy

07

D

C07D 223/16 (2006.01) A61K 31/40 (2006.01) A61K 31/47 (2006.01) A61K 31/55 (2006.01) C07D 209/42 (2006.01) C07D 215/38 (2006.01) C07D 215/48 (2006.01) C07D 243/12 (2006.01)

Patent

CA 2061662

RAN 4060/158 Abstract The novel compounds of the formula Image I wherein R1 signifies hydrogen, lower-alkyl or a cation; R2 signifies hydrogen, lower-alkyl, lower-alkoxy or halogen; M signifies -CONH- or -NHCO-; X and Y signify >CR3R4 or -CONR5-; Z signifies >CR6R7; R3, R4, R6 and R7 signify hydrogen or lower-alkyl; R5 signifies alkyl; and n signifies 0, 1 or 2; with the proviso that at least one residue X or Y is -CONR5- and this residue is bonded to the phenyl ring via the N atom can be used in the treatment and prophylaxis of neoplasms, dermatoses and aging skin.

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