Adjuvant and vaccine compositions containing monophosphoryl...

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61K 39/02 (2006.01) A61K 39/09 (2006.01) A61K 39/12 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2333578

The invention pertains to adjuvant and vaccine compositions of monophosphoryl lipid A, sugar and optionally an amine based surfactant, which when frozen and thawed or lyophilized and reconstituted reform a colloidal suspension having a light transmission of greater than or equal to 88% as measured spectrophotometrically.

L'invention concerne des compositions d'adjuvants et de vaccins à base de lipide monophosphoryle A, de sucre et éventuellement d'un tensio-actif à base d'amines qui, une fois gelées et dégelées ou lyophilisées et reconstituées, reforment une suspension colloïdale possédant une transmission de lumière supérieure ou égale à 88 % telle que mesurée par spectrophotométrie.

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