C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) C40B 40/08 (2006.01) C40B 40/10 (2006.01) G01N 33/574 (2006.01) A61K 39/00 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2516128
The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
L'invention concerne de nouvelles séquences à utiliser pour la détection, pour le diagnostic et pour le traitement de cancers, en particulier de lymphomes. L'invention concerne des séquences polynucléotidiques associées au cancer (CA), dont l'expression est associée au cancer. L'invention concerne des polypeptides CA associés au cancer, situés sur la surface cellulaire, et de nouvelles cibles thérapeutiques contre le cancer. L'invention concerne également des compositions et des méthodes de diagnostic pour la détection du cancer. L'invention concerne des anticorps monoclonaux et polyclonaux spécifiques aux polypeptides CA. L'invention concerne également des outils de diagnostic, des compositions et des méthodes thérapeutiques pour le criblage, la prévention et le traitement du cancer.
Malandro Marc S.
Morris David W.
Borden Ladner Gervais Llp
Sagres Discovery Inc.
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