A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4365 (2006.01) A61K 31/41 (2006.01) A61K 31/4184 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2332608
A method is provided for preventing a cerebral infarction by administering to a patient a combination of an ADP-receptor blocking antiplatelet drug, such as clopidogrel, in combination with an antihypertensive agent such as an angiotensin AII antagonist (for example, irbesartan), an ACE inhibitor (for example, fosinopril) or a NEP/ACE inhibitor such as omapatrilat.
L'invention concerne un procédé permettant de prévenir l'infarctus cérébral en administrant à un patient un anti-agrégant plaquettaire bloquant les récepteurs d'ADP, tel que du clopidogrel, combiné avec un agent antihypertenseur, tel qu'un antagoniste de l'angiotensine AII (par exemple, l'irbesartane), un inhibiteur de l'enzyme de conversion de l'angiotensine (par exemple, le fosinoprile) ou un inhibiteur de l'enzyme de conversion de l'angiotensine et de l'endopeptidase neutre (par exemple, l'omapatrilate).
Blumenthal Melvin S.
Coniglio Anthony A.
Plat Francis R.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
Sanofi-Synthelabo
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