High throughput automatic nucleic acid isolation and...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C12N 15/10 (2006.01) G06F 17/00 (2006.01) G06F 17/10 (2006.01)

Patent

CA 2502822

A high throughput RNA laboratory protocol is provided for the extraction and maintenance of a sufficient quantity of high quality RNA during sample preparation in order to analyze several genes at a time with assistance of computer analysis. The subject invention includes a method for analyzing RNA comprising the steps of extracting RNA from a complex biological construct in sufficient quantities to provide accurate RNA data, transferring RNA to an apparatus that maintains the RNA and necessary reagents at a temperature of between about 0 to 10~ C, and analyzing RNA with a computer generated mathematical analysis of the data to access the presence of RNA and ultimately test the efficacy of a drug.

L'invention concerne un protocole de laboratoire extrêmement productif servant à extraire et à conserver une quantité suffisante d'ARN de haute qualité pendant la préparation d'un spécimen, dans le but d'analyser plusieurs gènes à la fois à l'aide d'une analyse informatique. L'invention concerne une méthode servant à analyser l'ARN et consistant à extraire cet ARN d'un produit de recombinaison biologique complexe en quantités suffisantes pour produire des données précises concernant l'ARN à transférer l'ARN jusqu'à un dispositif maintenant cet ARN et les réactifs nécessaires à une température située entre 0 et 10 ·C et à analyser l'ARN au moyen d'une analyse mathématique générée par ordinateur et des ces données afin de détecter la présence d'ARN et, enfin, de tester l'efficacité d'un médicament.

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