Compounds as kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/14 (2006.01) A61K 31/4709 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 491/113 (2006.01)

Patent

CA 2733250

The present invention relates to compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.

La présente invention concerne des composés de formule (I), des procédés pour les préparer, des compositions pharmaceutiques les contenant en tant qu'ingrédients actifs, des procédés pour le traitement d'états pathologiques associés à l'angiogenèse, comme des cancers associés aux protéines tyrosine kinases, leur utilisation comme médicaments destinés à être utilisés pour produire une inhibition des effets réducteurs de tyrosine kinases chez les animaux à sang chaud comme les humains.

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