Process and intermediate compounds for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/00 (2006.01) C07C 69/716 (2006.01) C07D 207/12 (2006.01) C07D 207/273 (2006.01) C07D 305/12 (2006.01) C07D 307/62 (2006.01) C07H 7/02 (2006.01)

Patent

CA 2415097

Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate nucleoside and nucleic acid synthesis.

Cette invention a trait à des procédés de préparation de pyrrolidones (7 et 8) et de pyrrolidines (9 et 10) à partir d'esters d'acide pentulosonique-tri-O-acétyl-D-érythro-4. Ces composés, qui sont des analogues de sucre aza de ribofuranoside-D sont des intermédiaires de médicaments régulant la synthèse de nucléosides et d'acides nucléiques.

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