Novel agents that modulate eph receptor activity

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/475 (2006.01) A61K 38/10 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/71 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2499580

Novel agents are described that bind to Eph receptors. Methods of using these agents to modulate the activity of Eph receptors, stimulate apoptosis, and deliver therapeutic agents are also described. Methods of screening for agents capable of selectively binding to Eph receptors are also described.

La présente invention concerne de nouveaux agents qui se lient aux récepteurs Eph. Cette invention concerne également des méthodes d'utilisation de ces agents pour moduler l'activité des récepteurs Eph, stimuler l'apoptose et administrer des agents thérapeutiques. Cette invention concerne enfin des méthodes de criblage d'agents capables de se lier sélectivement aux récepteurs Eph.

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