Phosphonic acid derivatives as inhibitors of protein...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/38 (2006.01) C07F 9/40 (2006.01) C07F 9/6518 (2006.01) C07F 9/653 (2006.01) C07F 9/6539 (2006.01)

Patent

CA 2393367

The invention encompasses the novel class of compounds represented by formula (I), which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and conditions related to diabetes.

L'invention concerne la nouvelle classe de composés représentés par la formule I. Ces composés sont des inhibiteurs de l'enzyme PTP-1.beta.. L'invention concerne également des compositions pharmaceutiques et des méthodes de traitement ou de prévention de maladies à médiation PTP-1.beta., notamment les diabètes, l'obésité et les états pathologiques associés aux diabètes.

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