Indole derivatives and drugs

Details Indole derivatives and drugs Indole derivatives and drugs

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2090037

2090037 9204347 PCTABSCORE2 A novel serotonin-antagonistic indolecarboxamide derivative represented by general formula (I) and a serotonin antagonist containing the same as the active ingredient wherein R1 represents lower alkyl and R2 hydrogen, halogen, lower alkyl or lower alkoxy. It is efficacious as a regulatory agent for gastrointestinal motility, a therapeutic agent for migraine, an antipsychotic drug, an antianxiety drug, etc., and also as an antidemential drug and a therapeutic agent for orthostatic hypotension.

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