Pyrazolopyridines as cyclin dependent kinase inhibitors

Details Pyrazolopyridines as cyclin dependent kinase inhibitors Pyrazolopyridines as cyclin dependent kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2499593

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Dans ses nombreux modes de réalisation, la présente invention concerne une nouvelle classe de composés de pyrazolo[1,5-a]pyridine utilisés comme inhibiteurs de kinases dépendantes des cyclines, les procédés de préparation de ces composés, des compositions pharmaceutiques contenant au moins un tel composé, des procédés de préparation de formulations pharmaceutiques contenant au moins un tel composé, et des procédés de traitement, de prévention, d'inhibition, ou d'amélioration d'au moins une maladie liée aux kinases dépendantes des cyclines à l'aide de ces composés ou compositions pharmaceutiques.

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