Nitrosated and nitrosylated phosphodiesterase inhibitors,...

A - Human Necessities – 61 – K

Patent

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A61K 31/165 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) C07D 207/24 (2006.01) C07D 207/46 (2006.01) C07D 211/72 (2006.01) C07D 211/84 (2006.01) C07D 213/72 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 213/83 (2006.01) C07D 233/28 (2006.01) C07D 233/30 (2006.01) C07D 233/32 (2006.01) C07D 233/38 (2006.01) C07D 277/22 (2006.01) C07D 279/04 (2006.01) C07D 279/06

Patent

CA 2339189

Disclosed are nitrosated and/or nitrosylated compounds of formulae (I)-(XIX) which are phosphodiesterase inhibitors and compositions comprising them. The invention also provides methods for treating or preventing sexual dysfunctions in males and females and also diseases induced by cGMP.

L'invention concerne des composés nitrosés et/ou nitrosylés représentés par les formules (I)-(XIX), lesquels sont des inhibiteurs de la phosphodiestérase. L'invention concerne également des méthodes de traitement ou de prévention des dysfonctions sexuelles chez les sujets masculins et féminins ainsi que des maladies induites par le GMP cyclique.

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