C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 38/33 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/72 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2257857
The present invention relates to drug screening assays, and diagnostic and therapeutic methods for the treatment of body weight disorders, such as obesity, anorexia and cachexia, utilizing the melanocortin 4-receptor (MC4-R) as the target for intervention. The invention also relates to compounds that modulate the activity or expression of the MC4-R, and the use of such compounds in the treatment of body weight disorders.
Analyses sélectives et procédés diagnostiques et thérapeutiques pour le traitement des troubles du poids corporel, tels que l'obésité, l'anorexie et la cachexie, qui sont basés sur le récepteur 4 de la mélanocortine (MC4-R) en tant que cible d'intervention. La présente invention concerne également des composés qui modulent l'activité ou l'expression de MC4-R et l'utilisation desdits composés dans le traitement des troubles du poids corporel.
Gu Wei
Huszar Dennis
Lee Frank
Millennium Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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