Crystallized oxalate decarboxylase and methods of use

Details Crystallized oxalate decarboxylase and methods of use Crystallized oxalate decarboxylase and methods of use

A - Human Necessities

61

K

A61K 38/51 (2006.01) C07K 1/30 (2006.01) C12N 9/88 (2006.01) C12N 9/98 (2006.01) C12Q 1/527 (2006.01) C30B 7/00 (2006.01) C30B 29/58 (2006.01)

Patent

CA 2659081

Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.

La présente invention concerne des cristaux d'oxalate décarboxylase, comprenant des cristaux stabilisés, tels que des cristaux entrecroisés d'oxalate décarboxylase. L'invention concerne également des procédés de traitement d'un trouble associé à une concentration élevée d'oxalate, utilisant les cristaux d'oxalate décarboxylase. L'invention décrit de plus des procédés de production de cristaux protéiques.

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