C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 38/22 (2006.01) C07K 14/575 (2006.01)
Patent
CA 2479163
The present invention relates to an antagonist or inhibitor of leptin signalling via the leptin receptor. The leptin antagonist binds to the leptin receptor, but is unable to induce JAK-STAT signal transduction via the leptin receptor. By binding to the leptin receptor, the leptin antagonist impairs binding of leptin to the leptin receptor and blocks leptin signalling.
Peelman Frank
Tavernier Jan
Fetherstonhaugh & Co.
Universiteit Gent
Vib Vzw
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