Sulfonamide derivatives as liver carnitine palmitoyl...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61K 31/47 (2006.01) A61P 3/10 (2006.01) C07D 215/58 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2672761

The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R1, R2, R3, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.

L'invention porte sur de nouveaux dérivés de sulfonamide de formule (I) dans laquelle R1, R2, R3, X et Y sont tels que définis dans la description et dans les revendications, ainsi que sur les sels et esters physiologiquement acceptables de ceux-ci. Ces composés inhibent L-CPT1 et peuvent être utilisés comme médicaments.

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