Iron-casein complex and process for preparing the same

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A23J 3/10 (2006.01) A23L 1/305 (2006.01) A61K 47/02 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2256599

An iron-casein complex which does not give an astringent taste peculiar to iron even upon heat sterilization and has a high iron-replenishing effect. It can be prepared by mixing three solutions, that is, a solution (A) containing carbonic acid, bicarbonic acid, or a mixture of them, a solution (B1) containing iron, and a solution (B2) containing a casein, in a suitable order. In this case, however, the coexistence of carbonic acid, bicarbonic acid and iron only should be avoided. The iron-casein complex contains 1 to 1,000 atoms of iron and at least one molecule of each of carbonic and bicarbonic acids per molecule of the casein, and does not give an astringent taste even upon heat sterilization. It has a higher antianemic effect than inorganic iron salts.

L'invention se rapporte à un complexe fer-caséine qui ne donne pas le goût astringent propre au fer même après stérilisation thermique et qui a des propriétés élevées d'apport en fer. Ledit complexe peut être préparé par mélange, dans un ordre approprié, de trois solutions: une solution (A) contenant de l'acide carbonique, de l'acide bicarbonique ou un mélange des deux; une solution (B1) contenant du fer; et une solution (B2) contenant une caséine. Dans ce cas, cependant, la coexistence d'acide carbonique, d'acide bicarbonique et de fer seuls doit être évitée. Ledit complexe contient de 1 à 1000 atomes de fer, au moins une molécule d'acide carbonique et au moins une molécule d'acide bicarbonique par molécule de caséine; il ne donne pas de goût astringent même après stérilisation thermique. Ledit complexe a des propriétés antianémiques supérieures à celles de sels de fer inorganique.

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