An orally-absorbed solid dose formulation for vancomycin

Details An orally-absorbed solid dose formulation for vancomycin An orally-absorbed solid dose formulation for vancomycin

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 38/14 (2006.01)

Patent

CA 2704194

An orally bioavailable pharmaceutical composition comprises at least 40% (w/w) vancomycin; a permeation en-hancer component comprising 0.1 to 10.0% (w/w) of a polyoxyethylene sorbitan fatty acid ester; and a particulate carrier onto which the permeation enhancer component is adsorbed.

L'invention porte sur une composition pharmaceutique biodisponible par voie orale qui comprend au moins 40 % de vancomycine (p/p) ; un composant amplificateur de perméation comprenant 0,1 à 10,0 % (p/p) d'un ester d'acide gras et de sorbitan polyoxyéthyléné ; et un support particulaire sur lequel le composant amplificateur de perméation est adsorbé.

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