Method of making amino acid acrylic monoesters and...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 215/24 (2006.01) A61K 6/083 (2006.01) C07C 227/18 (2006.01) C07C 229/24 (2006.01)

Patent

CA 2264160

A method and composition are disclosed for making dibasic amino acid monoesters useful in repair of teeth in which a dibasic amino acid is partially esterfied with an allylic acrylic compound in the presence of an acidic ion-exchange resin at ambient temperature. The invention also comprises cyclicizing the amino groups of the monoesters.

L'invention porte sur un procédé (et une composition) servant à l'obtention de monoesters dibasiques d'acides aminés utilisables pour les obturations dentaires selon lequel un acide aminé dibasique est partiellement estérifié par un composé allylique acrylique en présence d'une résine échangeuse d'ions à la température ambiante. L'invention porte également sur la cyclisation du groupe amino des monoesters.

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