Controlled release macrolide pharmaceutical formulations

Details Controlled release macrolide pharmaceutical formulations Controlled release macrolide pharmaceutical formulations

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/30 (2006.01) A61K 9/36 (2006.01) A61K 9/48 (2006.01) A61K 31/4745 (2006.01) A61K 31/70 (2006.01) A61K 31/7048 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2405918

Disclosed is an oral controlled release macrolide pharmaceutical formulation. In a preferred embodiment, the formulation comprises a citrate salt of a preferred macrolide, clarithromycin. Also disclosed are methods for preparing, isolating and characterizing soluble and stable citrate salt of macrolides and use thereof in all solid dosage forms of macrolides.

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