Peptide compositions and formulations and use of same

Details Peptide compositions and formulations and use of same Peptide compositions and formulations and use of same

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 8/64 (2006.01) A61K 8/67 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/39 (2006.01) A61Q 19/00 (2006.01) C07K 5/06 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01) C07K 5/107 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2322839

The present invention is directed to a composition which is used to enhance the softness, elasticity, or appearance of tissue. Specifically, the present invention is directed to a composition formulated from peptides which substantially correspond to those produced from thermolysing digestion of elastin. This formulation is preferably applied to human skin in a cosmetic or therapeutic formulation. The present composition specifically includes the known chemical modification of the peptides described herein, specifically carboxy and amino modification including the addition of amino acids to either end of the peptide fragments.

La présente invention concerne une composition utilisée pour accentuer la douceur, l'élasticité ou l'apparence des tissus. Plus particulièrement, cette invention concerne une composition formulée à partir de peptides qui correspondent énormément à ceux produits par la digestion de l'élastine par thermolysine. De préférence, cette formulation est contenue dans une formulation cosmétique ou thérapeutique appliquée sur la peau. Par ailleurs, cette invention comprend particulièrement la modification chimique connue des peptides décrite dans cette invention, particulièrement la modification carboxyle et amino telle que l'addition d'acides aminés à l'une des extrémités des fragments des peptides.

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