Use of ketoconazole and related substances in medicaments...

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2196174

The use of ketoconazole or molecules resembling ketoconazole but with some side-chains not affecting the biological activity compared to ketoconazole changed, for the manufacture of drugs for medical treatment of diabetes mellitus type II as well as for counteracting the other risk factors being part of the Metabolic Syndrome (also known as "the deadly quartet" or "Syndrome X" or the "Insulin Resistance Syndrome").

Utilisation de cétoconazole ou de molécules ressemblant à du cétoconazole mais avec quelques chaînes latérales, n'affectant pas l'activité biologique par rapport au cétoconazole, ce composé étant modifié pour produire des médicaments pour le traitement médical du diabète sucré de type II ainsi que pour contrecarrer les autres facteurs de risque associés au syndrome métabolique (également connu comme "quartette mortel" ou "syndrome X" ou "syndrome de résistance à l'insuline").

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