Pyridyl-bridgehead derivatives and their analogues,...

Details Pyridyl-bridgehead derivatives and their analogues,... Pyridyl-bridgehead derivatives and their analogues,...

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2317025

Pharmaceutical compositions include aryl substituted amine compounds, and in particular, carbon-linked aromatic azabicyclo compounds, and in particular, aromatic alkylene azabicyclo compounds and aromatic alkyl azabicyclo compounds of formula (I) and formula (II) capable of acting to inhibit function of certain nicotinic cholinergic receptors.

Cette invention se rapporte à une composition pharmaceutique contenant des composés amines à substitution aryle et, notamment, des composés azabicyclo aromatiques à liaison carbone et, en particulier, des composés azabicyclo alkylènes aromatiques et des composés azabicyclo alkyles aromatiques, représentés par la formule (I) et par la formule (II), cette composition ayant pour effet d'inhiber la fonction de certains récepteurs cholinergiques nicotiniques.

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