Production of human hemoglobin in transgenic pigs

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 35/14 (2006.01) C07K 1/18 (2006.01) C07K 14/805 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2137911

The present invention relates to the use of transgenic pigs for the production of human hemoglobin in which, in certain em- bodiments, the pig beta globin promoter is used to facilitate the expression of human hemoglobin. The transgenic pigs of the in- vention may be used as an efficient and economical source of cell-free human hemoglobin that may be used for transfusions and other medical applications in humans.

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