Pyrazole derivatives having crf antagonist activity

Details Pyrazole derivatives having crf antagonist activity Pyrazole derivatives having crf antagonist activity

C - Chemistry, Metallurgy

07

D

C07D 231/44 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 231/14 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 403/12 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2272136

Disclosed are pyrazole derivatives of the formula: (see formula I-b) (wherein R1 is hydrogen or a substituent such as NH2; R2 is hydrogen or a substituent such as SCH3; R3 is a cyclic group such as an optionally substituted phenyl; and R4 is a cyclic group such as a substituted phenyl) having corticotropin- releasing factor (CRF) antagonist activity and useful for treatment of diseases induced by CRF.

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