Heparin with average molecular mass

Details Heparin with average molecular mass Heparin with average molecular mass

A - Human Necessities

61

K

A61K 31/727 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2434393

The invention relates to a novel heparin having an average molecular weight within a range of from 10 to 11.5 kd, in particular, an average molecular weight of 10 kd. Said heparin is obtained by controlled depolymerization of unfractionated heparin and subsequent molecular filtration. Said heparin is used for the preparation of a medicament for the prophylaxis and therapy of thrombo-embolic processes and, inter alia, for the inhibition of coagulation in extracorporeal circulations.

L'invention concerne une nouvelle héparine présentant une masse molaire moyenne comprise entre 10 et 11,5 kd, notamment une masse molaire moyenne égale à 10,5 kd. Cette héparine s'obtient par dépolymérisation contrôlée d'héparine non fractionnée puis par filtration moléculaire. Cette nouvelle héparine est utilisée pour la production d'un médicament servant à la prophylaxie et la thérapie de processus thromboemboliques et, entre autres, pour inhiber la coagulation dans des circuits extra-corporels.

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