Treatment of liver diseases in which iron plays a role in...

Details Treatment of liver diseases in which iron plays a role in... Treatment of liver diseases in which iron plays a role in...

A - Human Necessities

61

K

A61K 31/4196 (2006.01) A61P 1/16 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2608709

The invention relates to the use of 4-[3,5-Bis-(2-hydroxyphenyl)-[1,2,4]- triazol-1-yl]benzoic acid (hereinafter referred to as "Compound I") for the manufacture of pharmaceutical compositions for the treatment of liver diseases in humans in which iron plays a role in pathogenesis, including viral diseases, such as chronic hepatitis C, optionally in conjunction with antiviral agents and for the treatment of non viral diseases, such as non- alcoholic steatohepatitis and non-alcoholic fatty liver disease.

L'invention concerne l'utilisation d'acide 4-[3,5-Bis-(2-hydroxyphényl)-[1,2,4]-triazol-1-yl]benzoïque (appelé ici "composé I") dans la fabrication de compositions pharmaceutiques utiles dans le traitement de maladies hépatiques humaines dans la pathogenèse desquelles le fer joue un rôle, notamment des maladies virales, telles que l'hépatite C chronique, facultativement associées à des agents antiviraux, et dans le traitement de maladies non virales, telles que la stéatohépatite non alcoolique et la stéatose hépatique non alcoolique.

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