C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/495 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2550283
Crystalline form of the p38 kinase inhibitor 2-{4-[3-(4-chloro-2-fluorophenyl)- 4-pyrimidin-4-yl-lH-pyrazol-5-yl]piperidin-1-yl}-2-oxoethanol can be used, is provided. The crystalline form is a hydrated crystalline form. Also provided are combinations and pharmaceutical compositions comprising the crystalline form, process for preparing the crystalline form and for preparing compositions comprising the crystalline form, in methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of the crystalline form of 1.
Forme cristalline de l'inhibiteur de p38 kinase, le 2-{4-[3-(4-chloro-2-fluorophényl)-4-pyrimidin-4-yl-1h-pyrazol-5-yl]pipéridin-1-yl}-2-oxoéthanol. Il s'agit de la forme cristalline hydratée. L'invention concerne également des associations et des compositions pharmaceutiques comportant ladite forme cristalline, un procédé de préparation de cette forme cristalline et de compositions la comprenant, et leur utilisation dans des méthodes de prophylaxie et/ou de traitement d'un état induit par la p38 kinase, consistant à administrer à un sujet une quantité thérapeutique efficace de ladite forme cristalline selon la formule (1).
Hoffmann Doug H.
Schartman Richard R.
Hoffmann Doug H.
Pharmacia Corporation
Schartman Richard R.
Smart & Biggar
LandOfFree
Crystalline form of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystalline form of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystalline form of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1483414