Prb2/p130 peptide inhibitors of cdk2 kinase activity

A - Human Necessities – 61 – K

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Details

A61K 38/16 (2006.01) A61K 38/17 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2301333

The present invention provides peptides of pRb2/p130 (see the Figure) or mutants or fragments thereof which inhibit cdk2 kinase activity. Methods of inhibiting cdk2 kinase activity in cells with these peptides are also provided.

La présente invention concerne des peptides de pRb2/p130 (voir figure) ou des mutants ou fragments de ceux-ci inhibant l'activité kinase cdk2. L'invention concerne également des procédés d'inhibition de l'activité kinase cdk2 dans des cellules à l'aide de ces peptides.

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