A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/711 (2006.01) A61K 31/7105 (2006.01) A61K 31/7115 (2006.01) A61K 39/39 (2006.01) A61P 31/14 (2006.01) C07H 21/00 (2006.01)
Patent
CA 2402268
The invention provides methods of preventing and/or treating infection by a respiratory virus such as respiratory syncytial virus (RSV), particularly reducing infection and/or one or more symptoms of respiratory virus infection. A polynucleotide comprising an immunostimulatory sequence (an "ISS") is administered to an individual which is at risk of bieing exposed to a respiratory virus, has been exposed to a respiratory virus or is infected with a respiratory virus. The ISS is administered without any antigens of the respiratory virus. Administration of the ISS results in reduced incidence and/or severity of one or more symptoms of respiratory virus infection.
Cette invention concerne des méthodes permettant de prévenir et/ou de traiter une infection provoquée par un virus respiratoire tel que le virus syncytial respiratoire, et en particulier d'atténuer une infection et/ou un ou plusieurs symptômes d'infection respiratoire virale. A un individu qui risque d'être exposé, a été exposé ou est infecté par un virus des voies respiratoires, on administre un virus qui renferme une séquence immunostimulatoire. Le polynucléotide qui renferme ladite séquence est administré sans antigène du virus. L'administration de cette séquence polynucléotidique immunomodulatoire se traduit par une baisse de l'incidence et/ou une moindre gravité de l'un ou de plusieurs symptômes de l'affection virale respiratoire.
Borden Ladner Gervais Llp
Dynavax Technologies Corporation
LandOfFree
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