Stable isotope labeled polypeptide standards for protein...

Details Stable isotope labeled polypeptide standards for protein... Stable isotope labeled polypeptide standards for protein...

G - Physics

01

N

G01N 33/48 (2006.01)

Patent

CA 2569311

This invention relates to proteins having an amino acid sequence containing several amino acid subsequences found in nature and wherein at least two different subsequences act as monitor sequences, said subsequences being part of at least one natural protein which is a target protein, wherein the end of each of said two different subsequences have a cleavage site that will be cleaved by the same site-specific proteolytic treatment to release said subsequences.

Cette invention concerne des protéines dont la séquence d'acides aminés contient plusieurs sous-séquences d'acides aminés présents dans la nature, deux sous-séquences au moins agissant comme séquences de surveillance. Ces sous-séquences font partie d'au moins une protéine naturelle qui est une protéine cible, l'extrémité de chacune de deux sous-séquences différentes possédant un site de clivage sur lequel un clivage sera provoqué par le même traitement protéolytique spécifique au site en vue de libérer lesdites sous-séquences.

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