C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 57/30 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01)
Patent
CA 2102530
The use of S(-)sodium 2-(4-isobutylphenyl)propionate (the sodium salt of S(+)- ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphe- nyl)propionate dehydrate. Processes to prepare S(-)sodium 2-(4- isobutylphenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.
Armitage Bernard J.
Coe Paul F.
Lampard John F.
Smith Alan
Mccarthy Tetrault Llp
The Boots Company Plc
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