Therapeutic agent

Details Therapeutic agent Therapeutic agent

C - Chemistry, Metallurgy

07

C

C07C 57/30 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01)

Patent

CA 2102530

The use of S(-)sodium 2-(4-isobutylphenyl)propionate (the sodium salt of S(+)- ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphe- nyl)propionate dehydrate. Processes to prepare S(-)sodium 2-(4- isobutylphenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.

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