Methods for the specific production of lysobactin fragments

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/06 (2006.01)

Patent

CA 2586706

The invention relates to methods for specifically producing lysobactin derivatives by means of combined chemical and enzymatic modifications. The invention particularly relates to a method for producing the lysobactin derivative 4-11 by chemically reducing and splitting the obtained products with the aid of chymotrypsin.

Procédé de production ciblée de dérivés de lysobactine par des modifications combinées chimiques et enzymatiques. La présente invention concerne en particulier un procédé de production de dérivé de lysobactine 4-11 par réduction chimique et par clivage par la chymotrypsine des produits obtenus.

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