Substituted azetidinone compounds, formulations and uses...

Details Substituted azetidinone compounds, formulations and uses... Substituted azetidinone compounds, formulations and uses...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2517573

The present invention provides substituted azetidinone compounds of formula (1), formulations and processes for preparing the same which can be useful for treating vascular conditions such as atherosclerosis or hypercholesterolemia, diabetes, obesity, stroke, demyelination and lowering plasma levels of sterols and/or stanols in a subject.

La présente invention concerne des composés d'azétidinone substitués, représentés par la formule (I), ainsi que des formulations et des procédés de préparation de ces composés pouvant être utiles pour traiter des affections vasculaires telles que l'athérosclérose ou l'hypercholestérolémie, le diabète, l'obésité, l'AVC et la démyélinisation et pour faire baisser les concentrations plasmiques de stérols et/ou de stanols chez un sujet.

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