Pharmaceutical compositions of tizoxanide and nitazoxanide

A - Human Necessities – 61 – K

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A61K 31/426 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01)

Patent

CA 2418634

A pharmaceutical composition containing as active agent at least one compound selected among the group consisting of formula (I) (see formula I) and formula (II) (see formula II) The active agent is preferably in the form of particles having a particle size smaller than 200µm and a mean particle size of greater than 10µm. The pharmaceutical compositions are preferably stabilized with at least one pharmaceutically acceptable acid. The pharmaceutical compositions are particularly useful for treatment of opportunistic infections in persons with comprised or suppressed immune systems, and in treatment of infections of trematodes.

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