C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/505 (2006.01) A61P 3/10 (2006.01) C07D 239/10 (2006.01) C07D 401/12 (2006.01) C07D 491/10 (2006.01) C07F 9/6506 (2006.01) C07F 9/6512 (2006.01)
Patent
CA 2396596
aP2 inhibiting compounds are provided having formula (I) wherein A, B, X, and Y are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide troglitazone and/or insulin.
L'invention porte sur des composés inhibant aP2 et ayant la formule (I) dans laquelle A, B, X et Y sont tels que décrits dans la demande. L'invention porte également sur un procédé de traitement des diabètes et des maladies apparentées, et notamment sur les diabètes de type II, ces procédés utilisant l'inhibiteur d'aP2 ou une combinaison de celui-ci et tout autre agent antidiabétique tel que la metformine, le glyburide, la troglitazone et/ou l'insuline.
Robl Jeffrey A.
Sulsky Richard
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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