Process for purifying (-)-.delta.9-trans-tetrahydrocannabinol

C - Chemistry – Metallurgy – 07 – D

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C07D 311/80 (2006.01)

Patent

CA 2549399

A preparative separation process wherein (-)-.DELTA.9-trans- tetrahydrocannabinol is separated from a mixture of cannabinoids is disclosed. The process comprises at least one chromatographic step wherein a mobile phase passes through a stationary phase. The stationary phase comprises a derivatised polysaccharide and the mobile phase comprises carbon dioxide.

La présente invention concerne un procédé de séparation préparative dans lequel un (-)-??9¿-trans-tétrahydrocannabinol est séparé d'un mélange de cannabinoïdes. Le procédé comprend au moins une étape chromatographique dans laquelle une phase mobile traverse une phase stationnaire. La phase stationnaire comprend un polysaccharide dérivé tandis que la phase mobile comprend un dioxyde de carbone.

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