A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/40 (2006.01) A61K 31/215 (2006.01) A61K 31/24 (2006.01) A61K 31/5377 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2712414
The present invention relates to a pharmaceutical composition in the form of a storage-stable solution for the parenteral administration of ultrashort-effective .beta.-adrenorecep-tor antagonists, comprising a) an ultrashort-effective .beta.-adrenoreceptor antagonist and/or a pharmaceutically acceptable salt thereof, b) water, and c) a cyclodextrin and/or a functional cyclodextrin derivative. The composition according to the invention has high stability, even without the presence of additional adiuvants.
L'invention concerne une composition pharmaceutique sous la forme d'une solution stable au stockage pour l'administration parentérale d'un antagoniste de ß-adrénorécepteur à action très brève, contenant : a) un antagoniste de ß-adrénorécepteur à action très brève et/ou un sel pharmaceutiquement acceptable de celui-ci; b) de l'eau; c) une cyclodextrine et/ou un dérivé fonctionnel de cyclodextrine. La composition selon l'invention présente une grande stabilité même en l'absence d'autres agents auxiliaires.
Aop Orphan Pharmaceuticals Ag
Sim & Mcburney
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