An oral formulation for gastrointestinal drug delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/24 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/496 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01)

Patent

CA 2352389

An oral formulation for gastrointestinal drug delivery which comprises an adhesion site-controlling layer for attaching the formulation to the selected site in the digestive tract, a drug-carrying layer for containing a drug and an adhesive and a protecting layer for protecting the drug in the drug-carrying layer, wherein the drug-carrying layer exists between the protecting layer and the adhesion site-controlling layer, and the adhesion site-controlling layer may attach to the protecting layer. The formulation can improve bioavailability of drugs which have low bioavailability.

Cette préparation orale servant à diffuser un médicament du tube digestif comprend une couche adhésive de contrôle de site pour fixer la préparation au site choisi dans le tube digestif, une couche de réception de médicament pour contenir un médicament et un adhésif, et une couche protectrice pour protéger le médicament dans la couche de réception de médicament. La couche de réception de médicament est située entre la couche protectrice et la couche adhésive de contrôle de site. La couche adhésive de contrôle de site peut se fixer à la couche protectrice. Cette préparation peut améliorer la biodisponibilité de médicaments ayant une biodisponibilité faible.

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