Mass spectrometer

H - Electricity – 01 – J

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

H01J 49/42 (2006.01)

Patent

CA 2628926

A method is disclosed of identifying parent ions by matching daughter ions found to be produced at substantially the same time that the parent ions elute from a mixture. Ions emitted from an ion source (1) are transmitted to a fragmentation device (4) comprising an Electron Capture Dissociation, an Electron Transfer Dissociation or a Surface Induced Dissociation fragmentation device. The fragmentation device (4) is alternately and repeatedly switched between a first mode wherein the ions are substantially fragmented to produce daughter ions and a second mode wherein the ions are not substantially fragmented. Mass spectra are taken in both modes. At the end of an experimental run parent and daughter ions are recognised by comparing the mass spectra obtained in the two different modes. Daughter ions are matched to particular parent ions on the basis of the closeness of fit of their elution times, and this enables parent ions then to be identified.

L'invention concerne un procédé permettant d'identifier des ions parents par mise en correspondance d'ions filles produits sensiblement simultanément à l'élution des ions parents d'un mélange. Les ions provenant d'une source d'ions (1) sont transmis à un dispositif de fragmentation (4) par dissociation par capture d'électrons, par dissociation par transfert d'électrons ou par dissociation induite par une surface. Ledit dispositif de fragmentation (4) passe de manière alternative et répétée d'un premier mode dans lequel les ions sont sensiblement fragmentés pour produire des ions filles à un second mode dans lequel les ions ne sont pas sensiblement fragmentés. On obtient des spectres de masse dans les deux modes. A la fin d'une expérience, on reconnaît les ions parents et les ions filles par comparaison des spectres de masse obtenus dans les deux différents modes. On établit une correspondance entre des ions filles et des ions parents particuliers en fonction du degré de correspondance de leur temps d'élution, ce qui permet ensuite d'identifier lesdits ions parents.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Mass spectrometer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mass spectrometer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mass spectrometer will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1488229

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.