C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) A01K 67/027 (2006.01) A61K 31/58 (2006.01) A61K 31/7036 (2006.01) A61P 21/04 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C12N 1/15 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/12 (2006.01) C12N 15/54 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2448186
A novel polypeptide and a novel polynucleotide encoding the same. This polypeptide, which is an SMG-1 belonging to the phosphatidyl-inositol kinase- associated kinase family, is useful in constructing a system for screening a remedy and/or a preventive for pathological conditions caused by the formation of an early transcription termination codon due to a nonsense mutation.
La présente invention concerne un nouveau polypeptide et un nouveau polynucléotide codant celui-ci. Ce polypeptide, qui est un SGM-1 appartenant à la famille des kinases liées à la kinase de phosphatidyl-inositol, est utilisé pour construire un système permettant de cribler un remède et/ou un agent de prévention pour des pathologies causées par la formation d'un codon stop de transcription précoce, due à une mutation de non-sens.
Fetherstonhaugh & Co.
Japan Science And Technology Agency
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